Jan scientific Inc is based in Seattle, USA and deals with protein crystal imaging and screening systems. The Jan scientific microscopes called the UVEX are a rapid, precise and non invasive method for differentiating between salt and protein crystals. The microscope is engineered as a robust, open-frame system that can grow organically to suit the owner's needs. Hardware and software upgrades are easy, reliable and straightforward, and upgrading an existing system is much less expensive than purchasing a totally new system.
The principle behind the equipment design is tryptophan fluorescence at 360 nm, following deep UV excitation at 280 nm, can form the basis of a rapid screening. UV imaging also makes it possible to simultaneously identify all the protein crystals in a drop. As methods like Microseed Matrix Screening gain currency, UV fluorescence imaging becomes particularly useful in rapidly distinguishing between protein and salt crystals.
Protein crystals that are only a few micrometers long and are too small to mount and align in the X-ray beam are readily detected in the crystallization drop using our microscope.
To know more about the functioning of the instrument, you could check out the following videos:
For more information please visit: www.janscientific.com